CRTC1 anticorps

N° du produit ABIN7073590

Cet anticorps anti-CRTC1 Polyclonal Lapin (ABIN7073590) détecte spécifiquement CRTC1 dans IHC et IF. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour CRTC1 anticorps (ABIN7073590)

Antigène: CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRTC1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CRTC1 anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse TORC1

Information d'application

Indications d'application: IHC/IF (M,R) 1:400-1:800

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CRTC1

Antigène: CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))

Autre désignation: TORC1

Sujet: CRTC1, also named as MECT1, TORC1, and WAMTP1, belongs to the TORC family. It is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. CRTC1 acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. It enhances the interaction of CREB1 with TAF4. CRTC1 regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. It is a potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.

ID gène: 382056

NCBI Accession: NP_001004062

UniProt: Q68ED7