DPYSL4 anticorps

N° du produit ABIN7073734

Détail du produit anti-DPYSL4 anticorps

Antigène: DPYSL4 (Dihydropyrimidinase-Like 4 (DPYSL4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPYSL4 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse CRMP3

Information d'application

Indications d'application: IHC/IF (H,M,R) 1:650-1:4000/1:650-1:1300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur DPYSL4

Antigène: DPYSL4 (Dihydropyrimidinase-Like 4 (DPYSL4))

Autre désignation: CRMP3 (DPYSL4 Produits)

Synonymes: anticorps CRMP3A, anticorps CRMP3B, anticorps crmp3, anticorps crmp3-a, anticorps MGC53768, anticorps DPYSL4, anticorps drp-4, anticorps ulip4, anticorps CRMP-3, anticorps CRMP3, anticorps DRP-4, anticorps ULIP4, anticorps AI173505, anticorps Crmp3, anticorps DPY4, anticorps Drp-4, anticorps Ulip4, anticorps Dpys4, anticorps dihydropyrimidinase like 4, anticorps dihydropyrimidinase like 4 L homeolog, anticorps dihydropyrimidinase-like 4, anticorps DPYSL4, anticorps dpysl4.L, anticorps dpysl4, anticorps Dpysl4

Sujet: CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum. It is cleaved by Calpain to produce a p54 N-terminal fragment. This cleavage product translocates to the nucleus and induces neuronal death in response to excitotoxicity and cerebral ischemia. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.

UniProt: O35098