DPYSL4 anticorps
Aperçu rapide pour DPYSL4 anticorps (ABIN7073734)
Antigène
Voir toutes DPYSL4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse CRMP3
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Indications d'application
- IHC/IF (H,M,R) 1:650-1:4000/1:650-1:1300
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- DPYSL4 (Dihydropyrimidinase-Like 4 (DPYSL4))
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Autre désignation
- CRMP3
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Sujet
- CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum. It is cleaved by Calpain to produce a p54 N-terminal fragment. This cleavage product translocates to the nucleus and induces neuronal death in response to excitotoxicity and cerebral ischemia. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
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UniProt
- O35098
Antigène
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