EEA1 anticorps
Aperçu rapide pour EEA1 anticorps (ABIN7073795)
Antigène
Voir toutes EEA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse EEA1
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Indications d'application
- IHC/IF (M,R) 1:2000-1:5000/1:1000-1:1500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- EEA1 (Early Endosome Antigen 1 (EEA1))
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Autre désignation
- EEA1
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Sujet
- Early endosomes are cytoplasmic compartments that function in receiving and sorting endocytosed proteins for vesicular transport. EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes. EEA1 has sequence homology to several yeast proteins that have been implicated in membrane trafficking, including Vps27, Fab1 and Vac1. Evidence suggests a possible role for EEA1 in mediating the regulatory effects of 3'-phosphoinositides on membrane trafficking.
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ID gène
- 216238
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NCBI Accession
- NP_001001932
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UniProt
- Q8BL66
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Pathways
- Toll-Like Receptors Cascades
Antigène
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