L’anticorps anti-EMAP-II/AIMP1 Polyclonal Lapin est utilisé pour la détection de EMAP-II/AIMP1 dans des échantillons de Humain. Il a été validé pour WB.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Antigène
EMAP-II/AIMP1
Autre désignation
EMAP II/AIMP1
Sujet
SCYE1(small inducible cytokine subfamily E, member 1) is also named as EMAP2, AIMP1. The human cDNA encodes a 312-amino acid polypeptide that the predicted 34- kDa precursor can be cleaved to produce an active 20- kDa product. SCYE1 is secreted as a result of various stimuli, including TNF-α, heat shock, and hypoxia, and that it acts as a multifunctional cytokine on both endothelial and immune cells. Defects in AIMP1 are the cause of leukodystrophy hypomyelinating type 3 (HLD3). It has 2 isoforms produced by alternative splicing and the protein can exsit as a dimer.