FOSB anticorps

N° du produit ABIN7073925

Détail du produit anti-FOSB anticorps

Antigène: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOSB est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse FOSB

Information d'application

Indications d'application: WB (H,M,R) 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur FOSB

Antigène: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Autre désignation: Fos B (FOSB Produits)

Synonymes: anticorps FOSB, anticorps zgc:92354, anticorps AP-1, anticorps G0S3, anticorps GOS3, anticorps GOSB, anticorps fra-2, anticorps FBJ murine osteosarcoma viral oncogene homolog B, anticorps FosB proto-oncogene, AP-1 transcription factor subunit, anticorps FBJ osteosarcoma oncogene B, anticorps FOSB, anticorps fosb, anticorps Fosb

Sujet: The FOS gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipperproteins that can dimerize with proteins of the JUN family (e.g., c-Jun, JunD), thereby forming thetranscription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. FosB and its truncated splice variants, ΔFosB and further truncated Δ2ΔFosB, are all involved in osteosclerosis, although Δ2ΔFosB lacks a knowntransactivation domain, in turn preventing it from affecting transcription through the AP-1 complex.

Poids moléculaire: 36 kDa

ID gène: 14282

NCBI Accession: NP_032062

UniProt: P13346