KSR1 anticorps
Aperçu rapide pour KSR1 anticorps (ABIN7074435)
Antigène
Voir toutes KSR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse KSR1
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Indications d'application
- WB (M,R) 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- KSR1 (Kinase Suppressor of Ras 1 (KSR1))
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Autre désignation
- KSR1
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Sujet
- KSR1 is a molecular scaffold and positive regulator of the Raf/MEK/ERK phosphorylation cascade. It was initially considered to be a protein kinase acting in the Ras pathway. KSR1 is required for maximal ERK activation induced by growth factors and by some cytotoxic agents. In resting cells, phosphorylated KSR1 is cytoplasmic and in stimulated cells, dephosphorylated KSR1 is membrane associated.
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Poids moléculaire
- 97 kDa
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ID gène
- 16706
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NCBI Accession
- NP_001335136
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UniProt
- Q61097
Antigène
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