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MED8 anticorps

MED8 Reactivité: Humain, Souris, Rat WB, IF, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7074582
  • Antigène Voir toutes MED8 Anticorps
    MED8 (Mediator Complex Subunit 8 (MED8))
    Reactivité
    • 34
    • 13
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 29
    • 5
    Lapin
    Clonalité
    • 30
    • 4
    Polyclonal
    Conjugué
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MED8 est non-conjugé
    Application
    • 27
    • 22
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
     Réactivité croisée
    Humain, Rat
    Purification
    Affinity purification
    Immunogène
    Recombinant protein corresponding to Mouse MED8
  • Indications d'application
    WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:600-1:1200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    MED8 (Mediator Complex Subunit 8 (MED8))
    Autre désignation
    MED8 (MED8 Produits)
    Synonymes
    anticorps ARC32, anticorps 2210021A15Rik, anticorps AB041805, anticorps MNCb-2386, anticorps zgc:76877, anticorps med8-a, anticorps mediator complex subunit 8, anticorps mediator complex subunit 8 L homeolog, anticorps component of RNA polymerase II, anticorps mediator complex subunit Med8, anticorps MED8, anticorps Med8, anticorps med8, anticorps med8.L
    Sujet
    MED8, a component of the Mediator complex, is a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. It plays a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins. MED8 has three isoforms with MW 19 kDa, 29 kDa and 33 kDa. And the ubiquitination form will be 38-43 kDa.
    Poids moléculaire
    29 kDa
    ID gène
    80509
    NCBI Accession
    NP_001277617
    UniProt
    Q9D7W5
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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