HLA-DP anticorps

N° du produit ABIN7074613

Cet anticorps anti-HLA-DP Polyclonal Lapin (ABIN7074613) détecte spécifiquement HLA-DP dans IF et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HLA-DP anticorps (ABIN7074613)

Antigène: HLA-DP (MHC Class II HLA-DP (HLA-DP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-DP est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-HLA-DP anticorps

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Human HLA-DP

Information d'application

Indications d'application: IHC/IF (H) 1:1200-1:2400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur HLA-DP

Antigène: HLA-DP (MHC Class II HLA-DP (HLA-DP))

Autre désignation: HLA-DP

Sujet: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

ID gène: 3113

NCBI Accession: NP_001229453

UniProt: P20036