Mitochondrial Inner Membrane Protease ATP23 Homolog (ATP23) anticorps

N° du produit ABIN7074637

Détail du produit

Antigène: Mitochondrial Inner Membrane Protease ATP23 Homolog (ATP23)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Application: Western Blotting (WB)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse XRCC6BP1/KUB3

Information d'application

Indications d'application: WB (M,R) 1: 1000-1: 2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détail du antigène

Antigène: Mitochondrial Inner Membrane Protease ATP23 Homolog (ATP23)

Autre désignation: XRCC6BP1/KUB3

Sujet: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 30 kDa

ID gène: 68876

NCBI Accession: NP_081134

UniProt: Q9CWQ3