MRPL12 anticorps
Aperçu rapide pour MRPL12 anticorps (ABIN7074638)
Antigène
Voir toutes MRPL12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Souris, Rat
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Purification
- Affinity purification
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Immunogène
- KLH conjugated Synthetic peptide corresponding to Human MRPL12
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Indications d'application
- WB (M,R) 1: 500-1: 1000, IHC/IF (H) 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))
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Autre désignation
- MRPL12
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Sujet
- MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes, and is encoded by a nuclear gene. The protein forms a homodimer, localizes predominantly to mitochondria and binds to the large mitochondrial ribosomal subunit. It is required for CycD/Cdk4- induced cell growth. In addition, forming a ribosomal stalk with MRPL7, MRPL12 is required for the recruitment of translation elongation factors Tu and G to the large ribosomal subunit . It also a part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation and/or ribosome biogenesis during human mitochondrial gene expression.
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Poids moléculaire
- 21 kDa
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ID gène
- 56282
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NCBI Accession
- NP_081480
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UniProt
- Q9DB15
Antigène
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