MLF1 anticorps
Aperçu rapide pour MLF1 anticorps (ABIN7074712)
Antigène
Voir toutes MLF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse Myeloid leukemia factor 1
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Indications d'application
- WB (M,R) 1:500-1:1000, IHC/IF (M,R) 1:1000-1:3000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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Autre désignation
- Myeloid leukemia factor 1
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Sujet
- Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
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Poids moléculaire
- 31 kDa
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ID gène
- 17349
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NCBI Accession
- NP_034931
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UniProt
- Q9QWV4
Antigène
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