Cet anticorps anti-NAD-ME Polyclonal Lapin (ABIN7074757) détecte spécifiquement NAD-ME dans IHC et IF.
L’anticorps est réactif avec des échantillons de Humain et Rat.
ME2(malic enzyme 2) is also named as NAD-ME and belongs to the malic enzymes family. ME1, ME2 are important for NADPH production, lipogenesis and glutamine metabolism, but ME2 has a more profound effect. ME2 is a genome-coded mitochondrial enzyme that converts malate to pyruvate and is involved in neuronal synthesis of the neurotransmitter γ-aminobutyric acid (GABA). This protein has 2 isoforms produced by alternative splicing with the MW of 65 kDa and 54 kDa.