PLSCR3 anticorps

N° du produit ABIN7075071

L’anticorps anti-PLSCR3 Polyclonal produit chez le Lapin a été validé pour WB. Il convient pour la détection de PLSCR3 dans des échantillons provenant de Souris et Rat. }

Aperçu rapide pour PLSCR3 anticorps (ABIN7075071)

Antigène: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLSCR3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PLSCR3 anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse PLSCR3

Information d'application

Indications d'application: WB (M,R) 1: 500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PLSCR3

Antigène: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Autre désignation: PLSCR3

Sujet: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Poids moléculaire: 32 kDa

ID gène: 70310

NCBI Accession: NP_001161969

UniProt: Q9JIZ9

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis