PLSCR3 anticorps
Aperçu rapide pour PLSCR3 anticorps (ABIN7075071)
Antigène
Voir toutes PLSCR3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse PLSCR3
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Indications d'application
- WB (M,R) 1: 500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
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Autre désignation
- PLSCR3
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Sujet
- PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.
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Poids moléculaire
- 32 kDa
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ID gène
- 70310
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NCBI Accession
- NP_001161969
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UniProt
- Q9JIZ9
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
Antigène
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