PTGDR anticorps

N° du produit ABIN7075206

L’anticorps anti-PTGDR Polyclonal produit chez le Lapin a été validé pour WB. Il convient pour la détection de PTGDR dans des échantillons provenant de Souris et Rat. }

Aperçu rapide pour PTGDR anticorps (ABIN7075206)

Antigène: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGDR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PTGDR anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse Prostaglandin D2 Receptor

Information d'application

Indications d'application: WB (M,R) 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PTGDR

Antigène: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Autre désignation: Prostaglandin D2 Receptor

Sujet: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate . Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR.

Poids moléculaire: 50 kDa

ID gène: 19214

NCBI Accession: NP_032988

UniProt: P70263

Pathways: Thromboxane A2 Receptor Signaling