MLLT10
Reactivité: Humain, Rat
WB, FACS, IHC (p), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC/IF (M,R) 1:600-1:1200
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Antigène
MLLT10
(Protein AF-10 (MLLT10))
Autre désignation
AF10
Sujet
Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation.