PTPN12 anticorps

N° du produit ABIN7075292

Cet anticorps Lapin Polyclonal détecte spécifiquement PTPN12 dans WB, IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PTPN12 anticorps (ABIN7075292)

Antigène: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PTPN12 anticorps

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse PTPN12

Information d'application

Indications d'application: WB (H,M,R) 1: 500-1: 800, IHC/IF (H,M,R) 1:1000-1:3000/1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PTPN12

Antigène: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Autre désignation: PTPN12

Sujet: The PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. The PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion. This suggests it has a regulatory role in controlling cell shape and mobility.

Poids moléculaire: 110 kDa

ID gène: 19248

NCBI Accession: NP_035333

UniProt: P35831