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PTPN12 anticorps

PTPN12 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7075292
  • Antigène Voir toutes PTPN12 Anticorps
    PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))
    Reactivité
    • 49
    • 9
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 43
    • 6
    Lapin
    Clonalité
    • 44
    • 5
    Polyclonal
    Conjugué
    • 31
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PTPN12 est non-conjugé
    Application
    • 43
    • 14
    • 14
    • 13
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Rat
    Purification
    Affinity purification
    Immunogène
    KLH conjugated Synthetic peptide corresponding to Mouse PTPN12
  • Indications d'application
    WB (H,M,R) 1: 500-1: 800, IHC/IF (H,M,R) 1:1000-1:3000/1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))
    Autre désignation
    PTPN12 (PTPN12 Produits)
    Synonymes
    anticorps PTP-PEST, anticorps PTPG1, anticorps P19-PTP, anticorps PTP-P19, anticorps Ptpg1, anticorps RKPTP, anticorps protein tyrosine phosphatase, non-receptor type 12, anticorps PTPN12, anticorps Ptpn12
    Sujet
    The PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. The PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion. This suggests it has a regulatory role in controlling cell shape and mobility.
    Poids moléculaire
    110 kDa
    ID gène
    19248
    NCBI Accession
    NP_035333
    UniProt
    P35831
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