P2RY12 anticorps

N° du produit ABIN7075321

Cet anticorps anti-P2RY12 est un anticorps Lapin Polyclonal détectant P2RY12 dans WB, IHC et IF. Adapté pour Souris et Rat.

Aperçu rapide pour P2RY12 anticorps (ABIN7075321)

Antigène: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P2RY12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-P2RY12 anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse P2Y12

Information d'application

Indications d'application: WB (M,R) 1:250-1:500, IHC/IF (M,R) 1:1000-1:3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur P2RY12

Antigène: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Autre désignation: P2Y12

Sujet: The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. Human platelets express two G protein-coupled nucleotide receptors, P2Y1 and P2Y12. P2Y12 is a receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. P2Y12 is an integral membrane protein involved in platelet aggregation. It is highly expressed in platelets, with lower levels in the brain, lung, appendix, pituitary and adrenal gland.

Poids moléculaire: 50 kDa

ID gène: 70839

NCBI Accession: NP_081847

UniProt: Q9CPV9