RANGRF anticorps

N° du produit ABIN7075362

L’anticorps Lapin Polyclonal anti-RANGRF a été validé pour IHC et IF. Il convient pour détecter RANGRF dans des échantillons de Souris et Rat.

Aperçu rapide pour RANGRF anticorps (ABIN7075362)

Antigène: RANGRF (RAN Guanine Nucleotide Release Factor (RANGRF))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANGRF est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RANGRF anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse MOG

Information d'application

Indications d'application: IHC/IF (M,R) 1:1000-1:3000/1:500-1:1500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur RANGRF

Antigène: RANGRF (RAN Guanine Nucleotide Release Factor (RANGRF))

Autre désignation: MOG1

Sujet: This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1. Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics (By similarity). Enhances the expression of SCN5A at the cell membrane in cardiomyocytes.

ID gène: 57785

NCBI Accession: NP_001272370

UniProt: Q9JIB0