RRAGB anticorps
Aperçu rapide pour RRAGB anticorps (ABIN7075379)
Antigène
Voir toutes RRAGB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Réactivité croisée
- Humain, Rat
-
Purification
- Affinity purification
-
Immunogène
- Recombinant protein corresponding to Mouse RRAGB
-
-
-
-
Indications d'application
- WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:2000-1:4000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
-
- RRAGB (Ras-Related GTP Binding B (RRAGB))
-
Autre désignation
- RRAGB
-
Sujet
- Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
-
Poids moléculaire
- 43 kDa
-
ID gène
- 245670
-
NCBI Accession
- NP_001004154
-
UniProt
- Q6NTA4
Antigène
-