RMND5A anticorps
Aperçu rapide pour RMND5A anticorps (ABIN7075401)
Antigène
Voir toutes RMND5A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse RMND5A
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Indications d'application
- IHC/IF (M,R) 1:1500-1:3000/1:600-1:1200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))
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Autre désignation
- RMND5A
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Sujet
- Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.
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ID gène
- 68477
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NCBI Accession
- NP_077250
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UniProt
- Q80YQ8
Antigène
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