RMND5A anticorps

N° du produit ABIN7075401

Détail du produit anti-RMND5A anticorps

Antigène: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RMND5A est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse RMND5A

Information d'application

Indications d'application: IHC/IF (M,R) 1:1500-1:3000/1:600-1:1200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur RMND5A

Antigène: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Autre désignation: RMND5A (RMND5A Produits)

Synonymes: anticorps CTLH, anticorps GID2, anticorps GID2A, anticorps RMD5, anticorps p44CTLH, anticorps 1110007A06Rik, anticorps AJ237586, anticorps AW125795, anticorps Gid2, anticorps MTA.D02.090, anticorps required for meiotic nuclear division 5 homolog A, anticorps RMND5A, anticorps Rmnd5a

Sujet: Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.

ID gène: 68477

NCBI Accession: NP_077250

UniProt: Q80YQ8