ARHGAP17 anticorps
Aperçu rapide pour ARHGAP17 anticorps (ABIN7075416)
Antigène
Voir toutes ARHGAP17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse ARHGAP17
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Indications d'application
- WB (M) 1:250-1:500, IHC/IF (R) 1:500-1:1500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))
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Autre désignation
- ARHGAP17
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Sujet
- ARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
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Poids moléculaire
- 81 kDa
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ID gène
- 70497
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NCBI Accession
- NP_001116112
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UniProt
- Q3UIA2
Antigène
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