SAV1 anticorps

N° du produit ABIN7075505

Cet anticorps Lapin Polyclonal détecte spécifiquement SAV1 dans IHC et IF. Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour SAV1 anticorps (ABIN7075505)

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAV1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SAV1 anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse SAV1

Information d'application

Indications d'application: IHC/IF (M,R) 1:200-1:1400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SAV1

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Autre désignation: SAV1

Sujet: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

ID gène: 64010

NCBI Accession: NP_071311

UniProt: Q8VEB2

Pathways: Stem Cell Maintenance