Sarcomeric alpha Actinin anticorps

N° du produit ABIN7075510

Cet anticorps anti-Sarcomeric alpha Actinin Polyclonal Lapin (ABIN7075510) détecte spécifiquement Sarcomeric alpha Actinin dans WB, IEM, IF et IHC. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour Sarcomeric alpha Actinin anticorps (ABIN7075510)

Antigène: Sarcomeric alpha Actinin

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Application: Western Blotting (WB), Immunoelectron Microscopy (IEM), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse alpha Actinin 2

Information d'application

Indications d'application: WB (M,R) 1:2000, IHC/IF ,IEM (M,R) 1:500-1:1000/1:2000/1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détail du antigène

Antigène: Sarcomeric alpha Actinin

Sujet: The primary function of alpha-actinin 2 is to crosslink filamentous actin molecules and titin molecules from adjoining sarcomeres at Z-discs, a function that is modulated by phospholipids. It is clear from studies by Hampton etal. that this crosslinking can assume a variety of conformations, with preferences for 60° and 120° angles. Alpha-actinin 2 also functions in docking signaling molecules at Z-discs, and additional studies have also implicated alpha-actinin 2 in the binding of cardiac ion channels, Kv1.5 in particular.

Poids moléculaire: 104 kDa

ID gène: 11472

NCBI Accession: NP_150371

UniProt: Q9JI91