SMYD2A anticorps
Aperçu rapide pour SMYD2A anticorps (ABIN7075581)
Antigène
Voir toutes SMYD2A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse SMYD2
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Indications d'application
- IHC/IF (M,R) 1:1000-1:4000/1:1000-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
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Autre désignation
- KMT3C/SMYD2
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Sujet
- Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.
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ID gène
- 226830
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NCBI Accession
- NP_081072
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UniProt
- Q8R5A0
Antigène
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