Cet anticorps anti-Stanniocalcin 1 Polyclonal Lapin (ABIN7075723) détecte spécifiquement Stanniocalcin 1 dans IHC et IF.
L’anticorps est réactif avec des échantillons de Souris et Rat.
STC1
Reactivité: Humain
IHC, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC/IF(M,R)1:400-1:800
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Antigène
Stanniocalcin 1 (STC1)
Autre désignation
Stanniocalcin 1/STC
Sujet
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.