STRADA anticorps

N° du produit ABIN7075730

Cet anticorps Lapin Polyclonal détecte spécifiquement STRADA dans WB, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour STRADA anticorps (ABIN7075730)

Antigène: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STRADA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-STRADA anticorps

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse STRAD

Information d'application

Indications d'application: WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:600-1:1200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur STRADA

Antigène: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Autre désignation: STRAD

Sujet: LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.

Poids moléculaire: 48 kDa

ID gène: 72149

NCBI Accession: NP_001239377

UniProt: Q3UUJ4

Pathways: AMPK Signaling