SUPT3H/SPT3 anticorps

N° du produit ABIN7075767

L’anticorps Lapin Polyclonal anti-SUPT3H/SPT3 a été validé pour WB, IHC et IF. Il convient pour détecter SUPT3H/SPT3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SUPT3H/SPT3 anticorps (ABIN7075767)

Antigène: SUPT3H/SPT3 (SUPT3H) (Suppressor of Ty 3 Homolog (SUPT3H))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUPT3H/SPT3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SUPT3H/SPT3 anticorps

Réactivité croisée: Souris, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Human SUPT3H

Information d'application

Indications d'application: WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SUPT3H/SPT3

Antigène: SUPT3H/SPT3 (SUPT3H) (Suppressor of Ty 3 Homolog (SUPT3H))

Autre désignation: SUPT3H

Sujet: The transcription of many RNA polymerase II-dependent genes requires Spt3, a member of the S. cerevisiae SAGA complex. Transcription from delta sequences, the long terminal repeats that flank yeast Ty elements, requires the yeast SPT3 gene. Spt3 and Spt20 work together to recruit TATA-box binding protein (TBP) to the core promoter allowing TBP to bind to SAGA-dependent promoters. Null mutations in the Spt3 gene cause defects in sporulation, diploid filamentous growth, and haploid invasive growth, indicating that Spt3 has an important role in both mating and development pathways in yeast. At the promoters of some genes including yeast HO, HIS3 and TRP3 genes, Spt3 inhibits binding of TBP, resulting in reduced transcription.

Poids moléculaire: 36 kDa

ID gène: 8464

UniProt: O75486