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SYTL2 anticorps

SYTL2 Reactivité: Humain, Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7075797
  • Antigène Voir toutes SYTL2 Anticorps
    SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 16
    • 1
    Lapin
    Clonalité
    • 16
    • 1
    Polyclonal
    Conjugué
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SYTL2 est non-conjugé
    Application
    • 17
    • 15
    • 12
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Rat
    Purification
    Affinity purification
    Immunogène
    Recombinant protein corresponding to Mouse SYTL2/SLP2
  • Indications d'application
    IHC/IF (H,M,R) 1:800-1:1600/1:600-1:1200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))
    Autre désignation
    SYTL2/SLP2 (SYTL2 Produits)
    Synonymes
    anticorps AI266830, anticorps Slp2, anticorps Slp2-a, anticorps Slp2-b, anticorps Slp2-c, anticorps Slp2-d, anticorps mKIAA1597, anticorps CHR11SYT, anticorps EXO4, anticorps SGA72M, anticorps SLP2, anticorps SLP2A, anticorps synaptotagmin-like 2, anticorps synaptotagmin like 2, anticorps Sytl2, anticorps SYTL2
    Sujet
    Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
    ID gène
    83671
    NCBI Accession
    NP_001035174
    UniProt
    Q99N50
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