SYTL2 anticorps
Aperçu rapide pour SYTL2 anticorps (ABIN7075797)
Antigène
Voir toutes SYTL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Réactivité croisée
- Humain, Rat
-
Purification
- Affinity purification
-
Immunogène
- Recombinant protein corresponding to Mouse SYTL2/SLP2
-
-
-
-
Indications d'application
- IHC/IF (H,M,R) 1:800-1:1600/1:600-1:1200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
-
- SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))
-
Autre désignation
- SYTL2/SLP2
-
Sujet
- Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
-
ID gène
- 83671
-
NCBI Accession
- NP_001035174
-
UniProt
- Q99N50
Antigène
-