TAL1 anticorps
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- Antigène Voir toutes TAL1 Anticorps
- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TAL1 est non-conjugé
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Application
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Réactivité croisée
- Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse Tal1
- Top Product
- Discover our top product TAL1 Anticorps primaire
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anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibody
TAL1 Reactivité: Humain, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Porc, Singe, Roussette (Chauve-souris) WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) antibodyTAL1 Reactivité: Humain WB, FACS, IF Hôte: Souris Monoclonal 4G10 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 1-114) antibodyTAL1 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 154-188) antibodyTAL1 Reactivité: Humain WB Hôte: Lapin Polyclonal RB50954 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 68-97) antibodyTAL1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB15312 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 236-285) antibodyTAL1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Porc, Singe, Roussette (Chauve-souris), Hamster WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (N-Term) antibodyTAL1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Porc WB Hôte: Lapin Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (acLys221), (acLys222), (acLys36), (acLys37) antibodyTAL1 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- IHC/IF (R) 1:800-1:1500/1:400-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
- Autre désignation
- Tal1 (TAL1 Produits)
- Synonymes
- anticorps SCL/tal-1, anticorps Scl, anticorps bHLHa17, anticorps tal-1, anticorps SCL, anticorps TCL5, anticorps scl, anticorps tcl5, anticorps SCL-alpha, anticorps SCL-beta, anticorps scl/tal1, anticorps zgc:85605, anticorps T cell acute lymphocytic leukemia 1, anticorps TAL bHLH transcription factor 1, erythroid differentiation factor, anticorps T-cell acute lymphocytic leukemia 1 S homeolog, anticorps T-cell acute lymphocytic leukemia 1, anticorps Tal1, anticorps TAL1, anticorps tal1.S, anticorps tal1
- Sujet
- Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase alpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.
- ID gène
- 21349
- NCBI Accession
- NP_001274317
- UniProt
- P22091
- Pathways
- Stem Cell Maintenance
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