Thyroglobulin anticorps

N° du produit ABIN7075900

Détail du produit anti-Thyroglobulin anticorps

Antigène: Thyroglobulin (TG)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thyroglobulin est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse Thyroglobulin

Information d'application

Indications d'application: IHC/IF (M,R) 1:3000-1:6000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur Thyroglobulin

Antigène: Thyroglobulin (TG)

Autre désignation: Thyroglobulin (TG Produits)

Synonymes: anticorps TG, anticorps cb717, anticorps AITD3, anticorps TGN, anticorps Tgn, anticorps cog, anticorps thyroglobulin, anticorps TG, anticorps tg, anticorps LOC701526, anticorps LOC701756, anticorps LOC100434297, anticorps Tg

Sujet: Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

ID gène: 21819

NCBI Accession: NP_033401

UniProt: O08710

Pathways: Thyroid Hormone Synthesis