TOP3B anticorps
Aperçu rapide pour TOP3B anticorps (ABIN7075940)
Antigène
Voir toutes TOP3B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse TOP3B
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Indications d'application
- WB (R) 1:800-1:1500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- TOP3B (Topoisomerase (DNA) III beta (TOP3B))
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Autre désignation
- TOP3B
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Sujet
- This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants.
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Poids moléculaire
- 97 kDa
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ID gène
- 21976
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NCBI Accession
- NP_001313505
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UniProt
- Q9Z321
Antigène
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