TMEM199 anticorps
Aperçu rapide pour TMEM199 anticorps (ABIN7075998)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse TMEM199
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Indications d'application
- WB (H,M,R) 1:2000-1:4000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- TMEM199 (Transmembrane Protein 199 (TMEM199))
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Autre désignation
- TMEM199
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Sujet
- TMEM199, also named as C17orf32, is a component of the complex sense antisense architecture (CSAGA).Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation . May be involved in Golgi homeostasis.
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Poids moléculaire
- 23 kDa
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ID gène
- 195040
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NCBI Accession
- NP_954669
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UniProt
- Q5SYH2
Antigène
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