TRIM26 anticorps

N° du produit ABIN7076014

Cet anticorps anti-TRIM26 est un anticorps Lapin Polyclonal détectant TRIM26 dans WB. Adapté pour Humain, Rat et Souris. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour TRIM26 anticorps (ABIN7076014)

Antigène: TRIM26 (Tripartite Motif Containing 26 (TRIM26))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM26 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRIM26 anticorps

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse TRIM26

Information d'application

Indications d'application: WB (H,M,R) 1:1000-1:1500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-TRIM26 (ABIN7076014)

Xu, Tan, Liu, Han, Ge, Zhang, Luo, Wang, Xue, Xiong, Wang, Zhang, Wang, Tian, Zhang, Meng, Dai, Kuang, Li, Lou, Hu, Liu, Kuang, Luo, Chang, Wang, Chai, Shi, Han: "Tripartite motif containing 26 prevents steatohepatitis progression by suppressing C/EBPδ signalling activation." dans: Nature communications, Vol. 14, Issue 1, pp. 6384, (2023) (PubMed).

Détails sur TRIM26

Antigène: TRIM26 (Tripartite Motif Containing 26 (TRIM26))

Autre désignation: TRIM26

Sujet: TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation.

Poids moléculaire: 63 kDa

ID gène: 22670

NCBI Accession: NP_001020770

UniProt: Q99PN3