UNC13A/Munc13-1 anticorps
Aperçu rapide pour UNC13A/Munc13-1 anticorps (ABIN7076146)
Antigène
Voir toutes UNC13A/Munc13-1 (UNC13A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Réactivité croisée
- Rat
-
Purification
- Affinity purification
-
Immunogène
- Recombinant protein corresponding to Mouse Munc13-1
-
-
-
-
Indications d'application
- WB (M,R) 1: 1000-1: 2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
-
- UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))
-
Autre désignation
- Munc13-1
-
Sujet
- Unc-13 homolog A (C. elegans) is a protein that in humans is encoded by the UNC13A gene.. This gene encodes a member of the UNC13 family. UNC13A plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool. It is particularly important in most glutamatergic-mediated synapses but not GABA-mediated synapses. It plays a role in dendrite formation by melanocytes and in secretory granule priming in insulin secretion.
-
Poids moléculaire
- 194 kDa
-
ID gène
- 382018
-
NCBI Accession
- NP_001025044
-
UniProt
- Q4KUS2
-
Pathways
- Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
Antigène
-