L’anticorps anti-UPK1A Polyclonal produit chez le Lapin a été validé pour IHC, WB et IF. Il convient pour la détection de UPK1A dans des échantillons provenant de Souris et Rat.
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This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Antigène
UPK1A
(Uroplakin 1a (UPK1A))
Autre désignation
Uroplakin Ia
Sujet
Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention . Uroplakin-1a (UPK1A) belongs to the tetraspanin (TM4SF) family. UPK1A plays an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane.