ZNF746 anticorps

N° du produit ABIN7076272

Cet anticorps anti-ZNF746 est un anticorps Lapin Polyclonal détectant ZNF746 dans WB, IHC et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ZNF746 anticorps (ABIN7076272)

Antigène: ZNF746 (Zinc Finger Protein 746 (ZNF746))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF746 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ZNF746 anticorps

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse PARIS

Information d'application

Indications d'application: WB (H) 1:500-1:1000, IHC/IF (M,R) 1:1500-1:3000/1:1500-1:3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur ZNF746

Antigène: ZNF746 (Zinc Finger Protein 746 (ZNF746))

Autre désignation: PARIS

Sujet: ZNF746, also named as PARIS, which belongs to the krueppel C2H2-type zinc-finger protein family. ZNF746 mainly localizes to the cytoplasm and probably translocates to the nucleus to repress selected genes. ZNF746 as a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. ZNF746 may act as a downstream effector of PRKN and contribute to neurodegeneration in Parkinson disease cases caused by defects in PRKN.

Poids moléculaire: 100 kDa

ID gène: 69228

NCBI Accession: NP_001156947

UniProt: Q3U133