Aperçu rapide pour Lambda-IgLC anticorps (FITC) (ABIN7076305)
Antigène
Lambda-IgLC
(lambda Light Chain (Lambda-IgLC))
Reactivité
Humain
Hôte
Souris
Clonalité
Monoclonal
Conjugué
Cet anticorp Lambda-IgLC est conjugé à/à la FITC
Application
Flow Cytometry (FACS)
Classe de qualité
GMP Grade (Analyte)
Clone
HP6054
Fonction
Anti-Lambda Light Chain FITC Antibody
Attributs du produit
The clone HP6054 specifically binds with both soluble and membrane bound human lambda light chain of immunoglobulin but not binds with the kappa light chain or heavy chain. Lambda light chains are primarily expressed on the surface of B cells in lymphoid tissues. Each B cell expresses only one class of light chain kappa or lambda. In serum of a healthy individual, the total kappa to lambda ratio is approximately 3:1 while measuring as intact whole antibodies or 1:1.5 while measuring as free light chains. Various clinical research data claim that any highly divergent ratio of kappa to lambda indicative of neoplasm. HP6054 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.
Purification
Purified
Pureté
>95 %
Immunogène
Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads
FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.