CD58 anticorps (PE)
Aperçu rapide pour CD58 anticorps (PE) (ABIN7076675)
Antigène
Voir toutes CD58 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- CD58 PE Antibody
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Attributs du produit
- The clone TS2/9 recognizes a 45-70 kD cell surface protein, currently known as CD58. It is a member of the immunoglobulin superfamily previously known as lymphocyte function-associated antigen 3 (LFA-3). Both hematopoietic and non-hematopoietic cells including B and T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts express CD58. CD58 has two isoforms and is highly expressed on antigen specific memory T cells and as well as dendritic cells. The CD58 mediates cellular adhesion and participates in signal transduction when it binds to its ligand, the CD2 antigen. Cellular interactions regulated by the CD58/CD2 antigens are involved in the antigen-independent adhesion pathway and cytotoxic T lymphocyte (CTL) activity.
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Purification
- Purified
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Pureté
- >95 %
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Immunogène
- Human cytolytic T cells
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Isotype
- IgG1, kappa
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Indications d'application
- FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD58
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Autre désignation
- CD58
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ID gène
- 965
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UniProt
- P19256
Antigène
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