Myeloperoxidase anticorps (FITC)

N° du produit ABIN7077551

L’anticorps Souris Monoclonal anti-Myeloperoxidase a été validé pour FACS. Il convient pour détecter Myeloperoxidase dans des échantillons de Humain.

Aperçu rapide pour Myeloperoxidase anticorps (FITC) (ABIN7077551)

Antigène: Myeloperoxidase (MPO)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Myeloperoxidase est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade

Clone: 8-9

Détail du produit anti-Myeloperoxidase anticorps (FITC)

Fonction: MPO FITC Antibody

Attributs du produit: The clone 8/9, a mouse monoclonal antibody selectively binds with myeloperoxidase (MPO), a glycoprotein present in the granules of myeloid cells. MPO is critical for an optimal oxygen-dependent microbicidal activity of myeloid cells. The MPO generally appears in the myeloblast stage of myeloid cell differentiation. It is the most common functional protein of myeloid cells and is involved in the process of inflammatory immune responses mediated by myeloid cells. The primary translation product of MPO undergoes glycosylation with the production of 89 kDa heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kDa MPO alpha-chain and the 14 kDa MPO beta-chain. MPO gene expression may serve as an additional marker for subclassification of acute leukemias and may be used to identify leukemic cells arrested at an early stage of the myeloid differentiation pathway.

Purification: Purified

Pureté: >95 %

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C, Conjugated antibodies should never be frozen.

Détails sur Myeloperoxidase

Antigène: Myeloperoxidase (MPO)

Autre désignation: MPO

ID gène: 4353

UniProt: P05164

Pathways: Chromatin Binding