CD42b anticorps

N° du produit ABIN7091171

Cet anticorps anti-CD42b est un anticorps Lapin Monoclonal détectant CD42b dans WB et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CD42b anticorps (ABIN7091171)

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD42b est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: E10H7

Détail du produit anti-CD42b anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CD42b

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CD42b

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Autre désignation: CD42b

Sujet:

Synonyms: Antigen CD42b alpha, BSS, CD 42b, CD42b alpha, CD42b antigen, GLYCOCALICIN, Glycoprotein Ib (platelet) alpha polypeptide, Glycoprotein Ibalpha, GP Ib alpha, GP1B, GP1BA, GPIb alpha, MGC34595, Platelet glycoprotein Ib alpha chain, Platelet glycoprotein Ib alpha polypeptide, Platelet membrane glycoprotein 1b alpha subunit.

Background: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010].

ID gène: 2811

UniProt: P07359