GDF11 anticorps
Aperçu rapide pour GDF11 anticorps (ABIN7091177)
Antigène
Voir toutes GDF11 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Homologie
- Human
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Immunogène
- Recombinant human GDF11.
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Indications d'application
- WB 1:300-5000
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Restrictions
- For Research Use only
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Concentration
- 0.5 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- GDF11 (Growth Differentiation Factor 11 (GDF11))
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Autre désignation
- BMP11
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Sujet
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Synonyms: GDF11, BMP 11, Bone morphogenetic protein 11, GDF 11, Growth differentiation factor 11, Growth/differentiation factor 11, GDF11_HUMAN.
Background: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
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ID gène
- 10220
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UniProt
- O95390
Antigène
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