HAND2 anticorps (AA 51-150) (Biotin)

N° du produit ABIN7091191

L’anticorps Lapin Polyclonal anti-HAND2 a été validé pour IHC (p). Il convient pour détecter HAND2 dans des échantillons de Souris et Rat.

Aperçu rapide pour HAND2 anticorps (AA 51-150) (Biotin) (ABIN7091191)

Antigène: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAND2 est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HAND2 anticorps (Biotin)

Épitope: AA 51-150

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HAND2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur HAND2

Antigène: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Autre désignation: HAND2

Sujet:

Synonyms: DHAND 2, dHAND, DHAND2, Ehand 2, Ehand2, FLJ16260, HAND 2, Hand2, autonomic nervous system and neural crest derivatives-expressed protein 2, heart, Basic helix loop helix transcription factor HAND2, bHLHa26, Class A basic helix-loop-helix protein 26, Deciduum, Deciduum heart autonomic nervous system and neural crest derivatives expressed protein 2 antibody HAND2_HUMAN, Heart and neural crest derivatives expressed 2, Heart and neural crest derivatives expressed protein 2, heart and neural crest derivatives expressed transcript 2, Heart- and neural crest derivatives-expressed protein 2, Hed, Highly similar to dHAND M musculus, MGC125303, MGC125304, Th 2, Th2, Thing 2, Thing2.

Background: Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity).

ID gène: 9464

UniProt: P61296

Pathways: Tube Formation, Feeding Behaviour