IL23R anticorps (AA 231-330) (HRP)

N° du produit ABIN7091283

Cet anticorps Lapin Polyclonal détecte spécifiquement IL23R dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour IL23R anticorps (AA 231-330) (HRP) (ABIN7091283)

Antigène: IL23R (Interleukin 23 Receptor (IL23R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL23R est conjugé à/à la HRP

Application: Western Blotting (WB)

Détail du produit anti-IL23R anticorps (HRP)

Épitope: AA 231-330

Réactivité croisée: Humain

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IL-23R

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Détails sur IL23R

Antigène: IL23R (Interleukin 23 Receptor (IL23R))

Autre désignation: IL-23R

Sujet:

Synonyms: IL23 Receptor, IL-23R, IL23R, interleukin 23 receptor, IL 23R, IL-23 receptor, IL23R_HUMAN, Interleukin-23 receptor.

Background: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Subunit : Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3.

ID gène: 149233

UniProt: Q5VWK5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation