MCMBP anticorps (AA 551-642) (Biotin)

N° du produit ABIN7091413

L’anticorps anti-MCMBP Polyclonal Lapin est utilisé pour la détection de MCMBP dans des échantillons de Humain. Il a été validé pour IHC (p) et IHC (fro).

Aperçu rapide pour MCMBP anticorps (AA 551-642) (Biotin) (ABIN7091413)

Antigène: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCMBP est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MCMBP anticorps (Biotin)

Épitope: AA 551-642

Fonction: MCM-BP Polyclonal Antibody, Biotin Conjugated

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MCM-BP

Isotype: IgG

Information d'application

Indications d'application: IHC-P(1:100-500), IHC-F(1:100-500)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MCMBP

Antigène: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Autre désignation: MCM-BP

Sujet:

Synonyms: C10orf119 , chromosome 10 open reading frame 119 , MCM-binding protein , MCM-BP , mcmbp , MCMBP_HUMAN , Mini-chromosome maintenance complex-binding protein , Minichromosome maintenance complex binding protein.

Background: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP, probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.

ID gène: 79892

UniProt: Q9BTE3

Pathways: Chromatin Binding