ELAC2 anticorps (AA 88-190) (Biotin)

N° du produit ABIN706273

Détail du produit anti-ELAC2 anticorps (Biotin)

Antigène: ELAC2 (ElaC Homolog 2 (ELAC2))

Épitope: AA 88-190

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELAC2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ELAC2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ELAC2

Antigène: ELAC2 (ElaC Homolog 2 (ELAC2))

Autre désignation: ELAC2 (ELAC2 Produits)

Synonymes: anticorps 1110017O07Rik, anticorps D11Wsu80e, anticorps Hpc2, anticorps ELC2, anticorps HPC2, anticorps elaC ribonuclease Z 2, anticorps ELAC2, anticorps Elac2

Sujet:

Synonyms: elaC homolog 2, ElaC homolog protein 2, ELC2, Heredity prostate cancer protein 2, HPC2, putative prostate cancer susceptibility protein HPC2/ELAC2, Ribonuclease Z2, RNase Z2, tRNA 3 endonuclease 2, tRNase Z long form, tRNase Z2, Zinc phosphodiesterase ELAC protein 2.

Background: ELAC2 is a zinc phosphodiesterase which displays some tRNA 3' processing endonuclease activity. It is thought to be involved in tRNA maturation, acting by removing a 3' trailer from precursor tRNA. ELAC2 also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. A number of allelic variants have been investigated in hereditary prostate cancer.

ID gène: 60528