CD46 anticorps (AA 35-328)

N° du produit ABIN7092945

Cet anticorps Lapin Monoclonal détecte spécifiquement CD46 dans FACS et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD46 anticorps (AA 35-328) (ABIN7092945)

Antigène: CD46

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Clone: DM145

Détail du produit anti-CD46 anticorps

Épitope: AA 35-328

Fonction: Anti-CD46 antibody(DM145), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human CD46(Cys35-Asp328) (ABIN6964079) produced by using human HEK293 cells

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur CD46

Antigène: CD46

Autre désignation: CD46

Sujet: Synonyms:CD46,AHUS2,MCP,MIC10,TLX,TRA2.10
Description:The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Poids moléculaire: 43.7KDa

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization