RAD21 anticorps (AA 531-631)

N° du produit ABIN706391

Détail du produit anti-RAD21 anticorps

Antigène: RAD21 (RAD21 Homolog (RAD21))

Épitope: AA 531-631

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD21 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Rad2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RAD21

Antigène: RAD21 (RAD21 Homolog (RAD21))

Autre désignation: RAD21 (RAD21 Produits)

Synonymes: anticorps rad21, anticorps wu:fb55d02, anticorps wu:fb93f04, anticorps CDLS4, anticorps HR21, anticorps HRAD21, anticorps MCD1, anticorps NXP1, anticorps SCC1, anticorps hHR21, anticorps mKIAA0078, anticorps hr21, anticorps mcd1, anticorps nxp-1, anticorps nxp1, anticorps scc1, anticorps xrad21, anticorps RAD21 cohesin complex component, anticorps RAD21 cohesin complex component a, anticorps RAD21 cohesin complex component L homeolog, anticorps RAD21 cohesin complex component S homeolog, anticorps R-spondin 2, anticorps RAD21, anticorps rad21a, anticorps rad21.L, anticorps Rad21, anticorps rad21.S, anticorps RSPO2

Sujet:

Synonyms: HR21, MCD1, NXP1, SCC1, CDLS4, hHR21, HRAD21, Double-strand-break repair protein rad21 homolog, Nuclear matrix protein 1, NXP-1, SCC1 homolog, RAD21, KIAA0078

Background: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

ID gène: 5885

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity