CD38 anticorps (AA 43-300) (Biotin)
Aperçu rapide pour CD38 anticorps (AA 43-300) (Biotin) (ABIN7092986)
Antigène
Voir toutes CD38 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 43-300
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Fonction
- Biotinylated Anti-CD38 antibody(DM28), Rabbit mAb
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Immunogène
- Recombinant human CD38 (Val43-IIe300)(ABIN6961077) produced by using human HEK293 cells
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Isotype
- IgG
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Indications d'application
- ELISA 1:5000-10000, Flow Cyt 1:100
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- CD38
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Sujet
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Synonyms:T10, cADPr hydrolase 1
Description:CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia. -
Poids moléculaire
- 34kDa
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ID gène
- 952
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UniProt
- P28907
Antigène
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